BDBM50257165 CHEMBL2324391

SMILES Cn1nccc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=JUCACKLNHTWUCA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257165   

TargetCytochrome P450 3A4(Human)
Icagen

Curated by ChEMBL
LigandPNGBDBM50257165(CHEMBL2324391)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257165(CHEMBL2324391)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257165(CHEMBL2324391)
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Icagen

Curated by ChEMBL
LigandPNGBDBM50257165(CHEMBL2324391)
Affinity DataIC50: 184nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257165(CHEMBL2324391)
Affinity DataIC50: 30nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed