BDBM50257210 CHEMBL2324742

SMILES Clc1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ncns2)c(c1)-c1ccn[nH]1

InChI Key InChIKey=HWZRSTGNKARGTN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257210   

TargetCytochrome P450 2C9(Human)
Icagen

Curated by ChEMBL
LigandPNGBDBM50257210(CHEMBL2324742)
Affinity DataIC50: 205nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257210(CHEMBL2324742)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Icagen

Curated by ChEMBL
LigandPNGBDBM50257210(CHEMBL2324742)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257210(CHEMBL2324742)
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257210(CHEMBL2324742)
Affinity DataIC50: 30nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed