BDBM50257271 CHEMBL493347::N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanamide

SMILES NS(=O)(=O)NCCCCCC(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=FURLAGKXPNAXQK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50257271   

TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257271(N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanam...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257271(N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanam...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257271(N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257271(N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC1 in human 293T cells after 16 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed