BDBM50257890 3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane::CHEMBL494773

SMILES C1NC2CN(CC12)c1cccnc1

InChI Key InChIKey=UYZGGVMCTYTMRJ-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257890   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human recombinant alpha4beta2 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at human recombinant alpha3beta4 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed