BDBM50257949 (1S,3R)-3-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyran-4-ylamino)-1-isopropyl-cyclopentanecarboxylic acid 3,5-bis-trifluoromethyl-benzylamide::CHEMBL493843

SMILES CC(C)[C@@]1(CC[C@H](C1)NC1CCS(=O)(=O)CC1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IRLMWZLGLGZBTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257949   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257949((1S,3R)-3-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyra...)
Affinity DataIC50: 631nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257949((1S,3R)-3-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyra...)
Affinity DataIC50: 631nMAssay Description:Antagonist activity at CCR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article