BDBM50257953 CHEMBL4101591

SMILES [H][C@]12CC[C@H](C)[C@@H](\C=C\c3ccc(cn3)-c3cccc(F)c3)[C@]1(C)CC[C@@H](O)C2(C)C

InChI Key InChIKey=SAZKXOYARLGAAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257953   

TargetProteinase-activated receptor 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50257953(CHEMBL4101591)
Affinity DataIC50: 650nMAssay Description:Antagonist activity at PAR1 in human platelet-rich plasma assessed as reduction in thrombin-stimulated platelet aggregation preincubated for 3 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50257953(CHEMBL4101591)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human PAR1 expressed in HEK293 cells co-expressing Galpha15 assessed as inhibition of haTRAP-induced calcium mobilization prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50257953(CHEMBL4101591)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at PAR1 in human platelet-rich plasma assessed as reduction in TRAP-stimulated platelet aggregation preincubated for 20 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed