BDBM50258130 4-fluoro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide::CHEMBL492369::cid_44573689

SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(F)cc2[nH]c1=O

InChI Key InChIKey=QMXFZMPBYFJYLO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258130   

TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50258130(CHEMBL492369 | cid_44573689 | 4-fluoro-N-(2-(4-(5-...)
Affinity DataIC50: 12nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50258130(CHEMBL492369 | cid_44573689 | 4-fluoro-N-(2-(4-(5-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258130(CHEMBL492369 | cid_44573689 | 4-fluoro-N-(2-(4-(5-...)
Affinity DataIC50: 375nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258130(CHEMBL492369 | cid_44573689 | 4-fluoro-N-(2-(4-(5-...)
Affinity DataIC50: 375nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay