BDBM50258278 4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)ethyl)-1H-imidazol-2-amine::CHEMBL494015

SMILES COc1ccc(cc1)C(Cc1cc(ccc1OC)[N+]([O-])=O)c1cnc(N)[nH]1

InChI Key InChIKey=SUQKMDURKUPPHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258278   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258278(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 3.40E+3nMpH: 6.5Assay Description:Inhibition of BACE1 at pH 6.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258278(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50: 5.70E+3nMpH: 4.5Assay Description:Inhibition of BACE1 at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed