BDBM50258279 4-(1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nitrophenyl)ethyl)-1H-imidazol-2-amine::CHEMBL522520

SMILES COc1ccc(cc1F)C(Cc1cc(ccc1OC)[N+]([O-])=O)c1cnc(N)[nH]1

InChI Key InChIKey=RFLOFHKRBGKCOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258279   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258279(4-(1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nit...)
Affinity DataIC50: 3.20E+3nMpH: 6.4Assay Description:Inhibition of BACE1 at pH 6.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed