BDBM50258499 CHEMBL4100751

SMILES COC(=O)\C=C\[C@H](CCc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=XMJYDAHUKTUSSP-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258499   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258499(CHEMBL4100751)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 30 min by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258499(CHEMBL4100751)
Affinity DataKi:  41nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258499(CHEMBL4100751)
Affinity DataIC50: 9.63E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15(pREP4) using Cbz-Phe-Arg-AMC as substrate by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2019
Entry Details Article
PubMed