BDBM50258626 (S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetamido)-7-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)heptanamide::CHEMBL466215

SMILES COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(N)=O)c3nc(c[nH]3)-c3ccc4ccccc4c3)c2c1

InChI Key InChIKey=QZLKZEZKQRUHEU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50258626   

TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 30nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 160nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 250nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 120nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258626((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of His-tagged HDAC8 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed