BDBM50258979 CHEMBL4100655

SMILES Nc1ncnc2n(nc(-c3cccc(F)c3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=NEIPNPWJQGINQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258979   

TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258979(CHEMBL4100655)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R mutant expressed in baculovirus expression system preincubated for 30 mins followed by ATP and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258979(CHEMBL4100655)
Affinity DataIC50: 130nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258979(CHEMBL4100655)
Affinity DataIC50: 130nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed