BDBM50259086 CHEMBL4076970

SMILES COc1ccc2N(CN(C(=O)c2c1)c1ccc(cc1)N1CCOCC1=O)C(=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=SKFDSULSEOUCON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259086   

TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50259086(CHEMBL4076970)
Affinity DataIC50: 42nMAssay Description:Inhibition of human factor 10a using substrate S-2765 preincubated for 30 mins followed by substrate addition measured after 20 mins by micro plate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50259086(CHEMBL4076970)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human thrombin using substrate S-2238 preincubated for 30 mins followed by substrate addition measured after 20 mins by micro plate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed