BDBM50259249 CHEMBL4095224

SMILES Clc1ccc(cc1)C(NC(=O)OCCCc1c[nH]cn1)c1ccc(Cl)cc1

InChI Key InChIKey=UYMBIBLZLAJMQD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259249   

TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259249(CHEMBL4095224)
Affinity DataKi:  14nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259249(CHEMBL4095224)
Affinity DataKi:  15nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259249(CHEMBL4095224)
Affinity DataKi:  258nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed