BDBM50259270 7-(2-chlorophenyl)-6-(4-chlorophenyl)-N,N-diethyl-4-(isopropylamino)pyrido[2,3-d]pyrimidine-2-carboxamide::CHEMBL466084

SMILES CCN(CC)C(=O)c1nc(NC(C)C)c2cc(-c3ccc(Cl)cc3)c(nc2n1)-c1ccccc1Cl

InChI Key InChIKey=OXXZOOQIIFAICN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259270   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259270(7-(2-chlorophenyl)-6-(4-chlorophenyl)-N,N-diethyl-...)
Affinity DataIC50: 150nMAssay Description:Inverse agonist activity at human cannabinoid CB1R expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259270(7-(2-chlorophenyl)-6-(4-chlorophenyl)-N,N-diethyl-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Binding affinity to human cannabinoid CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed