BDBM50259271 2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)-4-methoxypyrido[2,3-d]pyrimidine::CHEMBL513121

SMILES COc1nc(nc2nc(-c3ccccc3Cl)c(cc12)-c1ccc(Cl)cc1)C(C)(C)C

InChI Key InChIKey=JSMOMDVBSOQGAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259271   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259271(2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)...)
Affinity DataIC50: 7.5nMAssay Description:Inverse agonist activity at human cannabinoid CB1R expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259271(2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)...)
Affinity DataIC50: 8.40E+3nMAssay Description:Binding affinity to human cannabinoid CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed