BDBM50259366 (S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl}-2-(1-benzylimidazol-2-yl)-acetanilide::CHEMBL466088

SMILES CC(Cc1ccc(NC(=O)Cc2nccn2Cc2ccccc2)cc1)NC[C@H](O)COc1ccccc1

InChI Key InChIKey=HFHHNHNEBZCVRQ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50259366   

TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50259366((S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50259366((S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50259366((S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl...)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50259366((S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl...)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50259366((S)-4'-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed