BDBM50259368 4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-3-carboxamide::CHEMBL444683

SMILES CC(=O)C(=NNc1cccc(c1)-n1nc(C(=O)Nc2nnc(s2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=MUQOGOAKZLBBCE-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259368   

TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataKi:  200nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataKi:  300nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataIC50: 410nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataIC50: 550nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259368(4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylide...)
Affinity DataIC50: 590nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed