BDBM50259369 4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phenyl)-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-3-carboxamide::CHEMBL453931

SMILES [#6]-[#6](=O)-[#6](=[#7]\[#7]-c1cccc(c1)-n1nc(-[#6](=O)-[#7]-c2nnc(s2)S([#7])(=O)=O)c(-[#6](=O)-c2ccccc2)c1-c1ccccc1)\[#6](-[#6])=O

InChI Key InChIKey=HZQKAEXPKGLWPY-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259369   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataIC50: 85nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataKi:  122nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataIC50: 180nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataKi:  240nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataIC50: 360nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259369(4-Benzoyl-1-(3-((2,4-dioxopentan-3-yl)diazenyl)phe...)
Affinity DataIC50: 450nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed