BDBM50259371 CHEMBL445982::Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazol-1-yl)phenyl)diazenyl)-3-oxo-3-phenylpropanoate

SMILES CCOC(=O)C(=NNc1cccc(c1)-n1nc(C(=O)Nc2nnc(s2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=LRIVKGPGZZZPSZ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259371   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataIC50: 40nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataKi:  81nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataIC50: 97nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataIC50: 430nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataKi:  580nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50259371(Ethyl-2-((3-(4-benzoyl-5-phenyl-3-(5-sulfamoyl-1,3...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed