BDBM50259511 CHEMBL511232::endo-methyl 8-(bis(2-chlorophenyl)methyl)-3-(5-fluoropyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-ylcarbamate

SMILES COC(=O)NC1(C[C@H]2CC[C@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccc(F)cn1

InChI Key InChIKey=VENQODNWCYDESL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259511   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259511(endo-methyl 8-(bis(2-chlorophenyl)methyl)-3-(5-flu...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259511(endo-methyl 8-(bis(2-chlorophenyl)methyl)-3-(5-flu...)
Affinity DataKi:  887nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed