BDBM50259592 CHEMBL4080255

SMILES Brc1cccc2C(C(=O)Nc12)=C1Nc2ccccc2C1=N/OCCN1CCNCC1

InChI Key InChIKey=PIQGKECRXCSKSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259592   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50259592(CHEMBL4080255)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GST-tagged c-Src (unknown origin) expressed in insect cells using pEY as substrate preincubated with enzyme followed by [33...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50259592(CHEMBL4080255)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GST-tagged c-Src catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50259592(CHEMBL4080255)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant GST-tagged JAK2 catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-la...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed