BDBM50259643 CHEMBL4065491

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)NCc1cnccn1)B(O)O

InChI Key InChIKey=JZTQMQRUMQSZRC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259643   

TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50259643(CHEMBL4065491)
Affinity DataIC50: 50nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50259643(CHEMBL4065491)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50259643(CHEMBL4065491)
Affinity DataIC50: 790nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by fluorescence analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed