BDBM50260050 CHEMBL4069227

SMILES Oc1cc(OCc2ccc(COc3cc(O)cc4oc(c(O)c(=O)c34)-c3ccc(O)c(O)c3)cc2)c2c(c1)oc(c(O)c2=O)-c1ccc(O)c(O)c1

InChI Key InChIKey=UTWPNYOWYYTWNI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260050   

TargetPlasminogen(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50: 1.16E+5nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50: 2.67E+5nMAssay Description:Inhibition of human thrombin by using chromogenic substrate spectrozyme TH preincubated for 5 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of human F10a by using chromogenic substrate spectrozyme F10a preincubated for 5 mins followed by substrate addition by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibition of human F11a by using chromogenic substrate S-2366 preincubated for 5 mins followed by substrate addition by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed