BDBM50260630 2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imidazol-5-yl)-2-methylpiperazin-1-yl)ethanol::CHEMBL494219

SMILES CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)C(C)C1

InChI Key InChIKey=PHNRBVJUYTWJPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260630   

TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260630(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260630(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed