BDBM50260983 CHEMBL4089060

SMILES CCN([C@@H](C)Cc1noc(n1)-c1ccc(F)cn1)C(=O)c1cc(C)ccc1-n1nccn1

InChI Key InChIKey=WRTKUBDGKZTJTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260983   

TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260983(CHEMBL4089060)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260983(CHEMBL4089060)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed