BDBM50261937 CHEMBL468189::Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-carboxylate

SMILES COC(=O)c1nc(no1)C(=O)CCCCCCc1ccccc1

InChI Key InChIKey=KSTLTXZRYWRDSB-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50261937   

TargetNeutral cholesterol ester hydrolase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataKi:  7nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50261937(Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-ca...)
Affinity DataKi:  7nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed