BDBM50262384 CHEMBL4094315

SMILES ONC(=O)CCCCCCNc1ncnc2ccc(F)cc12

InChI Key InChIKey=FMRRKIJLNAMNDY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262384   

TargetHistone deacetylase 8(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50262384(CHEMBL4094315)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50262384(CHEMBL4094315)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50262384(CHEMBL4094315)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50262384(CHEMBL4094315)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells at -80 mV holding potential measured for 9 mins by Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed