BDBM50262477 CHEMBL476511::Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinate

SMILES COC(=O)c1cccc(n1)-c1nnc(s1)C(=O)CCCCCCc1ccccc1

InChI Key InChIKey=UYJNBRLVPVJXOT-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262477   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262477(Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262477(Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262477(Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262477(Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2...)
Affinity DataKi:  7.70nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed