BDBM50262768 CHEMBL4096279

SMILES [H][C@]12CC[C@]([H])(N1C)c1c(C2)sc(NC(=O)Nc2ccc(Cl)cc2)c1C(N)=O

InChI Key InChIKey=DAHGONXBHYVOPI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262768   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262768(CHEMBL4096279)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262768(CHEMBL4096279)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262768(CHEMBL4096279)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262768(CHEMBL4096279)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262768(CHEMBL4096279)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed