BDBM50262933 CHEMBL451358::[1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)phenyl-3-(2-methoxyethyl)]-1H-pyrrole

SMILES COCCc1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccc(F)cc1

InChI Key InChIKey=WVSCJHNPJSMDST-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262933   

TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed