BDBM50262964 CHEMBL4100144

SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@H](C)N(C1CC(CCc2nc3cc(ccc3[nH]2)C(C)(C)C)C1)C1CC(CCc2nc3cc(ccc3[nH]2)C(C)(C)C)C1

InChI Key InChIKey=NKRMCBFZYIJVPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262964   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50262964(CHEMBL4100144)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (2 to 416 residues) expressed in Escherichia coli assessed as reduction in histone H3 lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed