BDBM50263214 CHEMBL478667::N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine

SMILES Clc1ccc2c(NCCCNCCCCOc3cccc4[nH]c5ccccc5c34)c3CCCCc3nc2c1

InChI Key InChIKey=CMKFVCOUPURYTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263214   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 1.65nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 211nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed