BDBM50263215 CHEMBL473866::N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine

SMILES Clc1ccc2c(NCCCNCCCCCOc3cccc4[nH]c5ccccc5c34)c3CCCCc3nc2c1

InChI Key InChIKey=NFCKRAFHWQEUBC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263215   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 1.54nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed