BDBM50263478 CHEMBL4062461

SMILES ONC(=O)c1ccc(Cn2c3C4CCCC(=O)N4CCc3c3ccccc23)cc1

InChI Key InChIKey=AMHMTADRKQMPBW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263478   

TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263478(CHEMBL4062461)
Affinity DataKi:  30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263478(CHEMBL4062461)
Affinity DataKi:  1.68E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in baculovirus-infected insect cells using RHK(Ac)K(Ac)AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263478(CHEMBL4062461)
Affinity DataKi:  7.24E+3nMAssay Description:Inhibition of full length recombinant human C-terminal GST-tagged HDAC2 expressed in baculovirus-infected insect cells using RHKK(Ac)AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed