BDBM50263499 (R)-1-(1-(3-chloro-5-fluorophenyl)-3-(methylamino)propyl)-7-fluoro-3,3-dimethylindolin-2-one::CHEMBL514354

SMILES CNCC[C@@H](N1C(=O)C(C)(C)c2cccc(F)c12)c1cc(F)cc(Cl)c1

InChI Key InChIKey=VLIFAHMVTGLJCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263499   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263499((R)-1-(1-(3-chloro-5-fluorophenyl)-3-(methylamino)...)
Affinity DataIC50: 19nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263499((R)-1-(1-(3-chloro-5-fluorophenyl)-3-(methylamino)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed