BDBM50263516 CHEMBL450092::N4-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d]imidazol-1-yl)pyrimidin-4-yl)-2-methyl-N6-(2-morpholinoethyl)pyrimidine-4,6-diamine

SMILES Cc1nc(NCCN2CCOCC2)cc(Nc2cc(ncn2)-n2c(Nc3c(C)cccc3Cl)nc3ccccc23)n1

InChI Key InChIKey=SQUDMCTZEYADTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263516   

TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263516(N4-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d...)
Affinity DataIC50: 13nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263516(N4-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d...)
Affinity DataIC50: 13nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed