BDBM50263523 CHEMBL4066996::US11236046, Example 3

SMILES F[C@@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(ncn1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=KISLLAVVUQSKFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263523   

LigandPNGBDBM50263523(CHEMBL4066996 | US11236046, Example 3)
Affinity DataIC50: 97nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

LigandPNGBDBM50263523(CHEMBL4066996 | US11236046, Example 3)
Affinity DataIC50: 97nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

LigandPNGBDBM50263523(CHEMBL4066996 | US11236046, Example 3)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2020
Entry Details Article
PubMed