BDBM50263543 1'-[(1R)-1-(3-fluorophenyl)-3-(methylamino)propyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one::CHEMBL515614

SMILES CNCC[C@@H](N1C(=O)C2(CCCCC2)c2ccccc12)c1cccc(F)c1

InChI Key InChIKey=DWTJKIXZDHRVPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263543   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263543(1'-[(1R)-1-(3-fluorophenyl)-3-(methylamino)propyl]...)
Affinity DataIC50: 26nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263543(1'-[(1R)-1-(3-fluorophenyl)-3-(methylamino)propyl]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed