BDBM50263544 1'-[(1R)-3-(methylamino)-1-phenylpropyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one::CHEMBL476154

SMILES CNCC[C@@H](N1C(=O)C2(CCCCC2)c2ccccc12)c1ccccc1

InChI Key InChIKey=ILKQBHSHNTVIIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263544   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263544(1'-[(1R)-3-(methylamino)-1-phenylpropyl]-1',2'-dih...)
Affinity DataIC50: 53nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263544(1'-[(1R)-3-(methylamino)-1-phenylpropyl]-1',2'-dih...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed