BDBM50264003 CHEMBL4093348

SMILES CN1[C@@H](CCCNC(N)=O)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N(C)[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C1=O

InChI Key InChIKey=KNNZNIYGBLJIFV-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50264003   

TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50264003(CHEMBL4093348)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]SDF-1alpha from ACKR3 (unknown origin) expressed in CHO cells after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2020
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50264003(CHEMBL4093348)
Affinity DataEC50:  490nMAssay Description:Activation of YFP-tagged ACKR3 (unknown origin) expressed in HEK293E cells assessed as induction of Rluc-tagged beta-arrestin-2 recruitment after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2020
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50264003(CHEMBL4093348)
Affinity DataEC50:  501nMAssay Description:Activation of YFP-tagged ACKR3 (unknown origin) expressed in HEK293E cells assessed as induction of Rluc-tagged beta-arrestin-2 recruitment after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50264003(CHEMBL4093348)
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of [125I]SDF-1alpha from CXCR4 (unknown origin) expressed in HEK293 cells after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2020
Entry Details Article
PubMed