BDBM50264129 CHEMBL488782::N-(4-Chloro-3-fluorophenyl)-1-(3-chloropyridin-2-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide

SMILES Fc1cc(NC(=O)C2=CCN(CC2)c2ncccc2Cl)ccc1Cl

InChI Key InChIKey=XBRNNVOIGSDIGM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264129   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50264129(N-(4-Chloro-3-fluorophenyl)-1-(3-chloropyridin-2-y...)Copy SMILESCopy InChI

Affinity DataIC50: 78nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL