BDBM50264298 CHEMBL490201::N-(2-((4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)(methyl)amino)-2-oxoethyl)-1-benzyl-1H-benzo[d]imidazole-2-carboxamide

SMILES CN(Cc1ccc(cc1)C1=NCCN1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1

InChI Key InChIKey=SHKZPYVPIUETPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264298   

TargetB1 bradykinin receptor(Crab-eating macaque)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50264298(N-(2-((4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)(met...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Rat)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50264298(N-(2-((4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)(met...)
Affinity DataIC50: 155nMAssay Description:Antagonist activity at rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed