BDBM50264492 CHEMBL522589::trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-benzoimidazol-2-yl]-spiro[cyclohexane-1,1'-isobenzofuran]-3'-one

SMILES Cc1nc(no1)-c1ccc2[nH]c(nc2c1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21

InChI Key InChIKey=MCZKHQJCBIKESW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50264492   

TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk cells assessed as inhibition of NPY-induced calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed