BDBM50264664 CHEMBL491033::N-(4-tert-Butylphenyl)-1-(3-cyanopyridin-2-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide

SMILES CC(C)(C)c1ccc(NC(=O)C2=CCN(CC2)c2ncccc2C#N)cc1

InChI Key InChIKey=KRLDPRAMPYKNKA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264664   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50264664(N-(4-tert-Butylphenyl)-1-(3-cyanopyridin-2-yl)-1,2...)Copy SMILESCopy InChI

Affinity DataIC50: 78nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL