BDBM50264705 CHEMBL491241::N-(4-(2-Cyanopropan-2-yl)phenyl)-1-(3-(trifluoromethyl)pyridin-2-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide

SMILES CC(C)(C#N)c1ccc(NC(=O)C2=CCN(CC2)c2ncccc2C(F)(F)F)cc1

InChI Key InChIKey=JXEAJXWJKWGKFD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264705   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50264705(N-(4-(2-Cyanopropan-2-yl)phenyl)-1-(3-(trifluorome...)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
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