BDBM50265122 (+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-propylpiperidin-3-ylamino)-2-oxoethylcarbamoyl)-4-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide::CHEMBL449672

SMILES CCCN1CCC(NCc2ccc(SC)cc2)C(C1)NC(=O)CNC(=O)c1cc(ccc1NC(=O)N1CCCC1)C(F)(F)F

InChI Key InChIKey=JGMQOJSHZALBEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265122   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 8.70nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed