BDBM50265491 1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]ethane}-2-(N-oxymorphyldiglycoldiamide)ethane::CHEMBL509792

SMILES CN1CC[C@]23[C@H]4Oc5cc(O)cc(C[C@@H]1[C@]2(O)CC[C@@H]4NC(=O)COCC(=O)NCCNC(=O)COCC(=O)NCCOc1cccc(NC(=O)N[C@@H]2N=C(c4ccccc4)c4ccccc4N(C)C2=O)c1)c35

InChI Key InChIKey=YLANCCITSFOFMP-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50265491   

TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataEC50:  119nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed