BDBM50265675 4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one::CHEMBL495961

SMILES CN1CCN(Cc2ccc3nc([nH]c3c2)-c2c(N)c3ccccc3[nH]c2=O)CC1

InChI Key InChIKey=JVYWSDGZGNKUKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265675   

TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265675(4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-b...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265675(4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-b...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265675(4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-b...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed