BDBM50265778 CHEMBL517730::N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)butyl]isoquinoline-3-carboxamide

SMILES COc1cccc2[nH]c3CN(CCCCNC(=O)C4=NCc5ccccc5C4)CCc3c12

InChI Key InChIKey=BURMBJGIJZXZNP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50265778   

TargetD(3) dopamine receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50265778(N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]7OH-DPAT from dopamine D3 receptor expressed in Sf9 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50265778(N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)...)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50265778(N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)...)
Affinity DataKi:  149nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50265778(N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)...)
Affinity DataKi:  6.48E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50265778(N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed